Research

Area 5

Physiopathology and molecular bases in hematology.

Team leader

Strategic objectives

Epidemiological, genetic, molecular and physiopathological study of malignant hematological diseases and erythrocyte pathology.

Main lines of research


1. Molecular bases of apoptosis regulation induced by drugs in lymphoid neoplasms. Evaluation of new strategies for the treatment of these disorders.

2. Cytological, immunophenotypic and molecular study of malignant hematological diseases. Development of new technologies for the diagnosis and follow-up of minimum residual disease.

3. Promotion of cooperative strategies in the molecular diagnostic setting of leukemias and lymphomas.

4. Design and implementation of internal and external quality control programs.

5. Cutaneous T and B cell lymphomas. Clinical, histopathological and immunophenotypic study. Prognostic factors and epidemiology.

6. Molecular study of the congenital alterations of erythrocytes and of the physiopathological mechanisms intervening in the production and destruction of erythrocytes as a cause of anemia or erythrocytosis.

7. Genetic and epidemiological study of hemoglobin diseases and thalassemias.